P N De Aza
Miguel Hernández University, Spain
Title: Eutectoids: A new bioceramic materials for bone tissue engineering
Biography
Biography: P N De Aza
Abstract
Bone tissue engineering provides an alternative way to repair diseased or damaged tissue and to recover its original state and function. In the tissue engineering approach, a highly porous artificial material, or scaffold, is employed as a template to facilitate the cell attachment, proliferation, and differentiation. Therefore, these materials must satisfy the requirements of biocompatible, osteoconductivity, controlled degradation, and provide adequate mechanical properties. A new route for obtaining bioactive ceramic materials, to improve the ingrowth of new bone into implants (osseintegration), is presented. This consitits of attaining eutectoid structures from selected systems bearing in mind the different bioactive behaviour of the phases. To this purpose the subsystem silicocarnotite- α-tricalcium phosphate was chosen because of the
first is bioactive and the second resorbable. The eutectoid material is formed by lamellae type microstructure of alternate layers of silicocarnotite and α-triclacium phosphate. The eutectoid material, in vitro esperiments, tranforms dissolving the α-tricalcium phosphate phase and forming, by pseudomorphic transformation of the silicocarnotite lamellae, a porous structure of hydroxyapatite, that mimic porous bone. The procedure developed by the authors opens the opportunity to obtain a new family of bioactive materials, with improved osseointegration, for which the general name of bioeutectoid® is proposed.